Parental stress before, during, and after pediatric stem cell transplantation: a review article

C M J Vrijmoet-Wiersma1, R M Egeler, H M Koopman

  • 1Pediatric Department, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. c.m.j.vrijmoet-wiersma@lumc.nl

Insights

Parental stress during pediatric stem cell transplantation (SCT) peaks before and during the acute phase. Identifying at-risk parents early is crucial for providing necessary support throughout the SCT journey.

Area of Science:

  • Pediatric Hematology/Oncology
  • Child Psychology
  • Family Medicine

Background:

  • Pediatric stem cell transplantation (SCT) is a demanding treatment for children with serious health conditions.
  • Parents experience significant psychological distress throughout their child's SCT journey.
  • Understanding parental adaptation is vital for effective supportive care.

Purpose of the Study:

  • To conduct a literature review on parental distress and adaptation during pediatric SCT.
  • To identify risk and protective factors influencing parental psychological adjustment.
  • To synthesize current knowledge on parental stress before, during, and after SCT.

Main Methods:

  • Systematic literature search of PubMed, Web of Science, PsychInfo, and Picarta databases.
  • Inclusion criteria: articles published 1990-2009, focusing on parents of pediatric SCT patients, examining psychological outcomes, and in English.
  • Analysis of 18 selected articles on parental stress and adaptation.

Main Results:

  • Parental stress is highest in the pre-SCT period and during the acute phase of treatment.
  • Stress levels generally decrease after hospital discharge for most parents.
  • A subset of parents experience persistent elevated stress post-SCT, particularly those with high acute-phase stress.

Conclusions:

  • Psychosocial assessments are essential before, during, and after SCT to identify parents needing support.
  • Early identification of at-risk parents facilitates timely intervention and follow-up care.
  • Targeted support can mitigate long-term parental distress associated with pediatric SCT.
Abstract

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