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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Multiphase evaluation of myocardial bridging with dual-source computed tomography
Long Jiang Zhang1, Gui Fen Yang, Chang Sheng Zhou
1Department of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing, Jiangsu Province, China.
Acta Radiologica (Stockholm, Sweden : 1987)
|July 3, 2009
Summary
Dual-source CT (DSCT) enables dynamic evaluation of myocardial bridging (MB), a congenital anomaly. This study shows DSCT can visualize and quantify the "milking effect" of MB with high image quality.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Myocardial bridging (MB) is a congenital anomaly where a coronary artery segment tunnels through heart muscle.
- Multidetector-row computed tomography (MDCT) aids MB diagnosis.
- Dual-source CT (DSCT) offers potential for dynamic MB assessment throughout the cardiac cycle.
Purpose of the Study:
- To assess the feasibility of dynamic evaluation of myocardial bridging (MB) using dual-source CT (DSCT).
Main Methods:
- Forty-eight patients with left anterior descending artery MB were included.
- Multiphase reconstructions were performed using DSCT.
- Image quality was assessed, and systolic/diastolic phases were selected for analysis of milking effect and stenosis rate.
Main Results:
- Optimal systolic and diastolic phases were identified between 40-70% of the R-R interval.
- DSCT provided high image quality (scores ≥3) for dynamic MB visualization.
- The "milking effect" (systolic narrowing, diastolic dilatation) was visualized, with an average MB stenosis of 36+/-14%.
Conclusions:
- DSCT is feasible for high-quality dynamic assessment of myocardial bridging.
- The "milking effect" associated with MB can be visualized and quantified using DSCT.
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