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Diagnostic yield of oesophagogastroduodenoscopy in children with abdominal pain

K Thakkar1, L Chen, N Tatevian

  • 1The Section of Pediatric Gastroenterology, Hepatology and Nutrition at Baylor College of Medicine, Houston, TX 77030, USA. kthakkar@bcm.tmc.edu

Alimentary Pharmacology & Therapeutics
|July 4, 2009
PubMed

Insights

Oesophagogastroduodenoscopy (OGD) is valuable for diagnosing chronic abdominal pain in children, with a 38% diagnostic yield. This procedure helps identify conditions like reflux esophagitis and H. pylori infections.

Area of Science:

  • Pediatric Gastroenterology
  • Diagnostic Endoscopy

Background:

  • Abdominal pain is a common reason for pediatric oesophagogastroduodenoscopy (OGD).
  • Limited studies exist on the diagnostic outcomes of OGD in children presenting with abdominal pain.

Purpose of the Study:

  • To determine the diagnostic yield of OGD with biopsy in evaluating pediatric abdominal pain.
  • To characterize endoscopic and histological findings in children undergoing OGD for unexplained abdominal pain.

Main Methods:

  • Retrospective cross-sectional cohort study.
  • Involved children under 18 undergoing OGD for abdominal pain.
  • Data collected from January 2002 to June 2005 at two children's hospitals.

Main Results:

  • OGD yielded a diagnosis in 38.1% (454/1191) of procedures.
  • Common diagnoses included reflux esophagitis (23%), Helicobacter pylori (5%), and peptic ulcers (3%).
  • Male gender, older age, elevated CRP, and vomiting correlated with higher diagnostic yield.

Conclusions:

  • OGD is a valuable tool for evaluating chronic abdominal pain in children.
  • The overall diagnostic yield for OGD in this cohort was 38%.
  • Alarm symptoms and routine lab tests showed limited association with diagnostic yield.
Abstract

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