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Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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The two main cell types that...

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

iPS Cell Differentiation

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

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Related Experiment Video

Updated: Jun 21, 2026

Primary Culture of Dental Pulp Stem Cells

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Stem cells: therapeutic potential in dentistry.

Fernanda Nedel¹, Dárvi de Almeida André, Isabel Oliveira de Oliveira

¹School of Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil. fernandanedel@hotmail.com

The Journal of Contemporary Dental Practice

|July 4, 2009

Summary

Stem cell research shows promise for tooth regeneration. Advances in understanding tooth development and stem cell biology may lead to new treatments for tooth loss and bone defects.

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Area of Science:

Dental research
Regenerative medicine
Biotechnology

Background:

Stem cells isolated from dental pulp and periodontal ligament.
Dental pulp stem cells can form dentin-pulp complexes.
Tooth-like structures have been created using dental tissues and scaffolds.

Purpose of the Study:

Review current stem cell research for tooth generation.
Discuss the potential of stem cells in dentistry.

Main Methods:

Literature review of stem cell research in tooth regeneration.
Analysis of studies on dental stem cell differentiation and tissue engineering.

Main Results:

Dental stem cells show potential for forming tooth tissues.
Successful creation of tooth-like structures in experimental models.
Progress in understanding molecular regulation of tooth morphogenesis.

Conclusions:

Further research is needed to optimize conditions for tooth regeneration.
Stem cell research and tissue engineering offer future alternatives for treating tooth loss and defects.
Potential applications include regenerating enamel, dentin, pulp, and bone, and replacing entire teeth.