Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Pedigree Analysis01:35

Pedigree Analysis

Overview
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Comprehensive Clinical Decision Support System for the Early Diagnosis of Axial Spondyloarthritis: Multi-Sequence MRI, Clinical Risk Integration, and Explainable Segmentation.

Diagnostics (Basel, Switzerland)·2026
Same author

Bilateral Renal Artery Thrombosis in a Patient With Behçet's Disease Managed With Infliximab Infusions.

Cureus·2026
Same author

The Determining of Pesticide Residue Levels in Children Diagnosed with Acute Leukemia in Cukurova Region, Turkiye.

Asian Pacific journal of cancer prevention : APJCP·2025
Same author

Efficacy and Safety of CT-P13 as First- and Second-Line Treatment in Patients with Ankylosing Spondylitis.

Journal of clinical medicine·2024
Same author

Investigation of ADAMTS-13 levels in patients with COVID-19 infection.

Journal of infection in developing countries·2024
Same author

Dermatoscopic assessment of nailfold capillary structures in connective tissue diseases.

Archives of dermatological research·2024

Related Experiment Video

Updated: Jun 21, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Familial Behçet's disease.

Sema Yilmaz1, Kadriye Akar Cimen

  • 1Division of Rheumatology, Selcuklu Faculty of Medicine, Selcuk University, Vatan cad. Devrim sitesi B/Blok No.: 25/4, 42040, Selcuklu, Konya, Turkey. drsemayilmaznew@gmail.com

Rheumatology International
|July 4, 2009
PubMed
Summary

Behçet

Area of Science:

  • Rheumatology and Immunology
  • Genetics and Epidemiology of Autoimmune Diseases

Background:

  • Behçet's disease (BD) is a complex multisystemic vasculitis with unpredictable flares.
  • BD exhibits a unique global distribution, predominantly along the historical Silk Road.
  • The exact cause of Behçet's disease remains unknown, but genetic factors are suspected.

Observation:

  • A case study of a Behçet's disease patient with a significant family history is presented.
  • Four family members were identified as having Behçet's disease within this patient's lineage.

Findings:

  • This familial aggregation provides further evidence for a genetic predisposition in Behçet's disease.
  • The observation supports the hypothesis that inherited factors play a role in BD pathogenesis.

More Related Videos

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Related Experiment Videos

Last Updated: Jun 21, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Implications:

  • Understanding the genetic underpinnings of Behçet's disease is crucial for early diagnosis and management.
  • Further research into familial BD cases can elucidate specific genetic markers and transmission patterns.
  • This case highlights the importance of family history in diagnosing and understanding Behçet's disease.