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Updated: Jun 21, 2026

The Deese-Roediger-McDermott (DRM) Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory
Published on: January 31, 2017
Memory-prediction errors and their consequences in schizophrenia
Michael S Kraus1, Richard S E Keefe, Ranga K R Krishnan
1Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. michael.kraus@duke.edu
Abstract:
Cognitive deficits play a central role in the onset of schizophrenia. Cognitive impairment precedes the onset of psychosis in at least a subgroup of patients, and accounts for considerable dysfunction. Yet cognitive deficits as currently measured are not significantly related to hallucinations and delusions. Part of this counterintuitive absence of a relationship may be caused by the lack of an organizing principle of cognitive impairment in schizophrenia research. We review literature suggesting that a system of memory-based prediction is central to human perception, thought and action , and forward the notion that many of the symptoms of schizophrenia are a result of a failure of this system.
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