Effect of older maternal age on the risk of spontaneous preterm labor: a population-based study

Safina Hassan McIntyre1, Christine V Newburn-Cook, Beverley O'Brien

  • 1Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.

To determine if older maternal age (35 years and older) at first birth was an independent risk factor for spontaneous preterm labor, we conducted a retrospective population-based cohort study. Using provincial perinatal data, we developed separate risk models for low- and high-risk women using multivariate logistic regression. We found that older maternal age exerted a direct and independent effect on spontaneous preterm labor for both nulliparous women with no preexisting chronic illnesses or pregnancy complications (low-risk) and nulliparous women who did not have any preexisting chronic illnesses, but developed one or more pregnancy complications (high-risk).

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