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Updated: Jun 21, 2026

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
Published on: February 4, 2016
Neuromodulation of epileptic foci in patients with non-lesional refractory motor epilepsy
Ana Luisa Velasco1, Francisco Velasco, Marcos Velasco
1Unit of Stereotactic, Functional Neurosurgery and Radiosurgery, Hospital General de México, Mexico City. analuisav@yahoo.com
Abstract:
We report two cases of chronic therapeutic stimulation of epileptic foci localized in motor areas. Case 1 is an adolescent with supplementary motor area seizures whose intracranial recordings showed a right SMA focus. Case 2 is a female teenager with primary motor seizures originating in the right motor cortex in the hand area as shown by her intracranial recordings and cortical mapping. Both had apparently normal MRI. Chronic stimulation of the epileptic focus decreased the number of seizures more than 90% the seizure number while preserving motor function. None of the patients had side effects. Neuromodulation is proposed as a safe, efficient surgical alternative for motor seizure control.
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