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Updated: Jun 21, 2026

Measuring Psoriasis Severity at Home

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Staphylococcus aureus and hand eczema severity.

P Haslund¹, N Bangsgaard, J O Jarløv

¹Department of Dermatology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark. phaslund@dadlnet.dk

The British Journal of Dermatology

|July 7, 2009

Summary

Staphylococcus aureus (S. aureus) bacteria were found on the hands of nearly half of hand eczema (HE) patients, and its presence correlated with increased disease severity. This suggests S. aureus may be a key factor in persistent hand eczema.

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Last Updated: Jun 21, 2026

Measuring Psoriasis Severity at Home

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

Dermatology
Microbiology
Infectious Diseases

Background:

The role of bacterial infections in hand eczema (HE) requires further investigation.
Assessing the prevalence of Staphylococcus aureus (S. aureus) in HE patients is crucial for understanding disease pathogenesis.

Purpose of the Study:

To determine the prevalence of S. aureus in patients with HE compared to controls.
To investigate the relationship between S. aureus presence, subtypes, toxin production, and HE severity.

Main Methods:

Bacterial swabs collected from hands and noses of 50 HE patients and 50 controls across three visits.
Staphylococcus aureus subtyped using spa typing and assigned to clonal complexes (CCs).
Isolates tested for exotoxin production; Hand Eczema Severity Index used for severity assessment.

Main Results:

S. aureus found on hands in 24 HE patients vs. four controls (P < 0.001), significantly related to increased eczema severity (P < 0.001).
Identical S. aureus strains found in hands and nose in all patients, and between visits in 90% of cases.
Ten CC types identified, with no association to severity; toxin-producing strains not more frequent in HE patients.

Conclusions:

Staphylococcus aureus is present on hands in nearly half of HE patients and is significantly associated with disease severity.
The association between S. aureus and hand eczema suggests it may be an important cofactor in the persistence of HE.