Related Experiment Video
Updated: Jun 21, 2026

Nasal Wipes for Influenza A Virus Detection and Isolation from Swine
Published on: December 4, 2015
Virulence of classical swine fever virus isolates from Europe and other areas during 1996 until 2007
G Floegel-Niesmann1, S Blome, H Gerss-Dülmer
1EU Reference Laboratory for CSF, Institute for Virology, University of Veterinary Medicine Hannover, Hannover, Germany. gundula_niesmann@yahoo.de
Abstract:
Classical Swine Fever (CSF) has caused several outbreaks in EU Member States with grave economic consequences. Several times the diagnosis of CSF was made too late partially due to non-specific clinical signs which did not raise suspicion for CSF. Virulence of CSF virus isolates (CSFV) still remains a subject of discussion and speculation as sufficient knowledge is still not available. Six uncharacterised CSFV isolates from 1996 to 2007 were assessed in animal experiments for their clinical virulence in order to broaden the knowledge about circulating CSFV and thereby assist disease eradication. A clinical (CS) and pathological score was applied and further extended by additional parameters to a modified CS (mCS) including case fatality, antibody production and leukocyte count. The unknown CSFV isolates could be classified as moderately or highly virulent. The inclusion of additional parameters, especially case fatality, into the mCS gave a more reliable classification of virulence, proving that there are clinical signs and laboratory parameters of blood which can be recognised. Therefore a subclinical course of infection is unlikely, especially in weaner pigs.
More Related Videos
08:10Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
Published on: January 15, 2020
04:18A Seamless Cloning Approach for Porcine Reproductive and Respiratory Syndrome Virus Expression Vector Construction
Published on: May 17, 2024
Related Concept Videos
Viral Recombination
Poliomyelitis
Viral Mutations
Rabies