Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jan 28, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Hodgkin lymphoma.

Bertram Schnitzer¹

¹Department of Pathology, University of Michigan, Ann Arbor, MI 48109-5602, USA. raven@med.umich.edu

Hematology/Oncology Clinics of North America

|July 7, 2009

Summary

This summary is machine-generated.

This review covers Hodgkin lymphoma, a rare cancer with unique clinical and histological features. It details the classification, diagnosis, and differential diagnosis of this distinct hematologic malignancy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pediatric extranodal marginal zone B-cell lymphoma presenting as amyloidosis in minor salivary glands: a case report and review of the literature.

Journal of pediatric hematology/oncology·2013

Same author

Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues.

Archives of pathology & laboratory medicine·2011

Same author

Clusterin expression in cutaneous CD30-positive lymphoproliferative disorders and their histologic simulants.

Journal of cutaneous pathology·2009

Same author

Site-specific morphologic differences in extranodal marginal zone B-cell lymphomas.

Archives of pathology & laboratory medicine·2007

Same author

Fascin expression in diffuse large B-cell lymphoma, anaplastic large cell lymphoma, and classical Hodgkin lymphoma.

Archives of pathology & laboratory medicine·2007

Same author

Highly aggressive ALK-positive anaplastic large cell lymphoma with a leukemic phase and multi-organ involvement: a report of three cases and a review of the literature.

Annals of hematology·2007

Same journal

Palliative Therapy for Liver and Biliary Neoplasms.

Hematology/oncology clinics of North America·2026

Same journal

Ablative Therapies for Liver Tumors.

Hematology/oncology clinics of North America·2026

Same journal

Pathology of Liver and Biliary Neoplasms.

Hematology/oncology clinics of North America·2026

Same journal

Minimally Invasive Surgery for Liver and Biliary Tract Neoplasms.

Hematology/oncology clinics of North America·2026

Same journal

Surgical Considerations for Primary Liver Neoplasms.

Hematology/oncology clinics of North America·2026

Same journal

Systemic Therapy for Biliary and Liver Neoplasms: Chemotherapy and Immunotherapy.

Hematology/oncology clinics of North America·2026

See all related articles

Area of Science:

Oncology
Hematology
Pathology

Background:

Hodgkin lymphoma, first described over 175 years ago, presents unusual clinical and histomorphological features distinct from other malignancies.
Its incidence in the United States is approximately 7400 new cases annually, with an age-adjusted rate of 2.7 per 100,000 individuals.
Unlike non-Hodgkin lymphoma, the classification and organizational schemes for Hodgkin lymphoma have remained relatively stable over time.

Purpose of the Study:

To provide a comprehensive review of the classification systems for Hodgkin lymphoma.
To detail the diagnostic criteria and methods for identifying Hodgkin lymphoma.
To discuss the differential diagnosis of Hodgkin lymphoma, distinguishing it from other conditions.

Main Methods:

More Related Videos

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Published on: June 10, 2017

Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice

Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice

Published on: April 3, 2011

Related Experiment Videos

Last Updated: Jan 28, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Published on: June 10, 2017

Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice

Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice

Published on: April 3, 2011

Review of established medical literature and classification systems for Hodgkin lymphoma.

Analysis of clinical and histomorphological characteristics relevant to diagnosis.

Comparison with differential diagnoses based on current medical understanding.

Main Results:

Hodgkin lymphoma possesses unique pathological features that aid in its identification.
Stable classification schemes facilitate consistent diagnosis and understanding.
Differential diagnosis requires careful consideration of clinical presentation and histological findings.

Conclusions:

Accurate diagnosis of Hodgkin lymphoma relies on understanding its unique characteristics and established classification.
Distinguishing Hodgkin lymphoma from other conditions is crucial for appropriate patient management.
This review consolidates key information on Hodgkin lymphoma classification, diagnosis, and differential diagnosis.