Related Experiment Video
Updated: Jun 21, 2026

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects
Published on: June 24, 2025
Reference study on the time frame for ossification of the distal radius and ulnar epiphyses on the hand radiograph
U Baumann1, R Schulz, W Reisinger
1Institut für Rechtsmedizin, Charité - Universitätsmedizin Berlin, 10553 Berlin, Germany.
Abstract:
Hand radiographs from 554 male and 288 female subjects aged 10-30 years, which had been taken due to traumatological indications, were evaluated. A classification into five ossification stages was applied to assess the epiphyseal development of distal radius and distal ulna (1: epiphysis not ossified; 2: epiphysis ossified, nonunion of the epiphysis and metaphysis; 3: partial union of the epiphysis and metaphysis; 4: complete union of the epiphysis and metaphysis, epiphyseal scar visible; 5: complete union of the epiphysis and metaphysis, epiphyseal scar nondiscernable). It was established that male subjects with an ossification stage 4 of the radius or ulna and female subjects with an ossification stage 5 of the radius were at least 14 years old. The occurrence of ossification stage 5 of the radius proves that a male individual has reached the age of 18 years.
Related Concept Videos
Bones of the Upper Limb: Radius
The radius has a nail-shaped head, and a short...
Bones of the Upper Limb: Ulna
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Bones of the Upper Limb: Humerus
Bone Formation by Endochondral Ossification
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...