Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
Xianfeng Chen1, Tarl W Prow, Michael L Crichton
1Delivery of Drugs and Genes Group (D(2)G(2)), Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia.
Abstract:
Dry-coated microprojections (MPs) deliver vaccine to abundant immunogenic cells within the skin to induce immune responses. Success in this targeted vaccine delivery relies on overcoming the challenges of dry-coating the vaccine onto the very small (
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