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Updated: Jun 21, 2026

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
[Novel treatment possibilities for proximal caries]
Hendrik Meyer-Lueckel1, Ole Fejerskov, Sebastian Paris
1Klinik für Zahnerhaltungskunde und Parodontologie des Universi- tätsklinikums Schleswig-Holstein, Christian-Albrechts-Universität zu Kiel.
Summary
Novel minimally invasive dental treatments, including proximal sealing and caries infiltration, offer alternatives to traditional invasive caries lesion management. These advanced techniques show promise in preventing further lesion progression and may complement existing preventive and restorative options.
Area of Science:
- Dentistry
- Dental Materials Science
Context:
- Current caries treatment paradigms are dichotomized into non-invasive prevention and invasive lesion removal.
- Treatment thresholds for invasive interventions vary significantly among dental professionals and institutions.
- Limited invasive strategies for proximal caries are emerging but not yet universally adopted.
Purpose:
- To explore novel, minimally invasive approaches for managing dental caries lesions.
- To evaluate the potential of proximal sealing and caries infiltration as alternatives or adjuncts to traditional treatments.
- To bridge the gap between preventive measures and invasive surgical interventions in caries management.
Summary:
- Proximal sealing using conventional sealants demonstrates clinical efficacy in halting lesion progression and is recommended for practical application.
- Caries infiltration of enamel lesions on proximal and smooth surfaces shows potential, pending further clinical validation of in vitro findings.
- These limited invasive strategies aim to refine the current dichotomized approach to caries treatment.
Impact:
- These novel strategies may offer more conservative treatment options, preserving tooth structure.
- Successful implementation could lead to improved patient outcomes and reduced need for extensive restorative procedures.
- The findings support the integration of minimally invasive techniques into standard dental practice for caries management.