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Updated: Jun 21, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Prostate cancer: evidence based clinical practice]
Leonardo Oliveira Reis1, André Deeke Sasse, Wagner Eduardo Matheus
1Sección de Urología Oncológica, Discipline of Urology, Universidad de Campinas-Unicamp, Campinas, SP, Brazil. reisleo@unicamp.br
This guideline provides evidence-based recommendations for prostate cancer treatment, aiding physicians in clinical decisions. It details the strength of evidence and degree of recommendation for various therapeutic options.
Area of Science:
- Urology
- Clinical Oncology
- Radiotherapy
Context:
- Evidence-based medicine (EBM) principles applied to prostate cancer.
- Systematic literature research for grading clinical evidence.
- Guideline development for healthcare professionals.
Purpose:
- To assist physicians and health professionals in making clinical decisions for prostate cancer treatment.
- To determine the strength of recommendation for external clinical evidence.
- To provide guidance on urological, clinical oncology, and radiotherapy interventions.
Summary:
- Utilized structured data searches in electronic databases (CENTRAL, MEDLINE) for information sources.
- Developed original questions and distributed them to participants for guideline content.
- Employed a formal ranking system with levels of evidence (LE) and degrees of recommendation (DR).
Impact:
- Recommendations serve as guidelines for clinical practice.
- Empowers physicians to make informed treatment decisions in consultation with patients.
- Facilitates the selection of the most suitable clinical procedure or treatment plan.
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