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Published on: May 22, 2018
[The influence of hemodialysis on heart's intraventricular conduction system--pilot study]
Dorota Polak-Jonkisz1, Krystyna Laszki-Szczachor, Danuta Zwolińska
1Medical University of Wroclaw, Department of Pediatric Nephrology. dpjonkisz@nefped.am.wroc.pl
Insights
Hemodialysis can cause cardiac conduction disturbances in children. Body surface heart potential mapping (BSPM) detects these changes earlier than standard ECG, and a single dialysis session can improve them.
Area of Science:
- Cardiology
- Pediatric Nephrology
- Biomedical Engineering
Context:
- Children undergoing hemodialysis are at high risk for cardiac complications.
- Assessing the impact of hemodialysis on cardiac electrodynamics in pediatric patients is crucial.
Purpose:
- To evaluate the influence of hemodialysis on cardiac electrodynamics in children and adolescents undergoing replacement therapy.
- To compare the diagnostic capabilities of Body Surface Potential Mapping (BSPM) with classic ECG in detecting cardiac changes.
Summary:
- Multielectrode recordings and isopotential maps were created before and after hemodialysis in pediatric patients.
- BSPM revealed early conduction disturbances and left ventricular hypertrophy, which were not detected by classic ECG.
- Hemodialysis led to improvements in cardiac electrodynamics, with BSPM showing normalization of some parameters.
Impact:
- BSPM is a more sensitive method for detecting early cardiac conduction system disturbances in pediatric hemodialysis patients compared to classic ECG.
- Findings suggest that hemodialysis can induce reversible changes in cardiac electrodynamics.
- This study highlights the importance of advanced cardiac monitoring in pediatric patients with kidney disease.
Unlabelled:
The highest percent of cardiac muscle damages is written down in children which are exposed to hemodialysis. In this group the heart examinations using body surface heart potential mapping (BSPM) method have been carried out. The aim of the study was to assess the influence of hemodialysis on heart's electrodynamics in children and adolescent during replacement therapy.
Material And Methods:
Multielectrode recording have been done in every kid before and after hemodialysis. For every record it was created isopotential map. By the comparing our maps with model maps for healthy children it was affirmed that in greater part of studied examples of hemodialysed children there are present early changes indicating conducting disturbances in left bundle of fasciculus atrioventricularis (His) and initial stage of left ventricular hypertrophy (LVH). That changes haven't been confirmed in classic ECG, which suggests that the disturbances in excitation conductance observed on isointegral maps are far beyond the area detected by 12-electrode classic ECG recording.
Results:
The maps made before dialysis are characterised by large, unsymmetrical isopotential lines changes over the left and right ventricle. After carried out of hemodialysis the image of ECG records was improving. In all of cases the isoline distribution in sternal and anterior lower left part of chest comes back to norm. Changes are visible merely over the left ventricle and in anterior upper right part of chest what is connected with just stabilised conducting disturbances in the left branch of His bundle, left bundle of fasciculus atrioventricularis (His bundle).
Conclusions:
1. In children who are treated by repeated hemodialysis approach to disturbances in the cardiac intraventricular conduction system. 2. Those disturbances are improved by a singular hemodialysis. 3. BSPM method detects earlier changes in the cardiac intraventricular conduction system than the classical ECG.
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