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Interrogating 7TM receptors: does texture in the question yield greater texture in the answer?

Terry Kenakin1

  • 1GlaxoSmithKline Research and Development, Research Triangle Park, North Carolina 27709, USA. Terry.P.Kenakin@gsk.com

Journal of Receptor and Signal Transduction Research
|July 8, 2009
PubMed
Summary

Pharmacological assays are crucial for drug discovery at seven transmembrane (7TM) receptors. Modern label-free live-cell assays offer superior ligand detection and efficacy characterization compared to older methods.

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