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Vasogenic edema in striatum following ingestion of glufosinate-containing herbicide
Hui-Young Lee1, Seo-Young Song, Seung-Hwan Lee
1Department of Internal Medicine, College of Medicine, Kangwon National University Hospital, Chuncheon, Kangwon-do, Korea.
Abstract:
Glufosinate-ammonium (GLA) is a broad-spectrum herbicide used worldwide. We report a patient who attempted suicide by ingesting a liquid herbicide containing GLA. A diffusion-weighted MRI showed cytotoxic edema in the hippocampus as well as vasogenic edema in the striata. To our knowledge, vasogenic edema caused by GLA-containing herbicide involving the striatum has not been reported in association with cytotoxic edema in the hippocampus. We assume that this herbicide affected the central nervous system via different mechanisms to produce both cytotoxic and vasogenic edema in the same patient.
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