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Updated: Jun 21, 2026

ABCG5/G8 Crystallization in a Lipidic Bicelle Environment for X-Ray Crystallography
Published on: August 25, 2023
Nonreciprocal XeCl laser-induced aggregation of beta-crystallins in water solution
Evgeny Chelnokov1, Lev Soustov, Natalia Sapogova
1Institute of Applied Physics, Russian Academy of Sciences, Nizhny Novgorod, Russia.
Abstract:
The aggregation of a beta-crystallin water solution exposed to XeCl laser radiation demonstrates the dependence of scattering-exposure curve (scattering versus exposure) on laser intensity. The main features of this dependence can be understood by the relaxation of a partly denaturated state of a protein within some finite relaxation time. These photoactivated states originate from the absorption of UV photons. Two partly denaturated (photoactivated) monomers, as well as other aggregates, can aggregate, giving rise to sharply increasing probe light scattering after some lag time of irradiation.
