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Updated: Jun 21, 2026
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Clinical data and hearing of individuals with Alport syndrome
Fatima Regina Abreu Alves1, Fernando de Andrade Quintanilha Ribeiro2
1PhD student in Otorhinolaryngology - Master in ENT - FCMSC-SP. Preceptor - ENT Ward - HSPM - SP.
Unlabelled:
Alport Syndrome (AS) is a hereditary disease, characterized by nephropathy, often times with sensorineural hearing loss and ocular defects.
Aim:
to analyze the clinical and hearing information from individuals with AS, more specifically the correlation between renal disorder and hearing loss (HL).
Study Design:
clinical prospective with cross-sectional cohort.
Materials And Methods:
37 individuals underwent otorhinolaryngological evaluation and were submitted to audiologic tests. For HL statistical analysis we considered only the results from the pure tone audiometries.
Results:
of the 28 individuals with clinical alterations, we found 46.4% of DLX and 53.6% of AD. HL happened to 46.1% of the individuals evaluated. 12 patients presented HL in the audiometric test: 11.5% mild and 34.6% moderate. Comparing the normal relatives with those with renal disorder; all that had HL also had renal disorder. In 30.8% the curve shape was mild descending in the high frequencies and in 11.5% it was flat.
Conclusions:
The inheritance pattern distribution does not match literature descriptions. HL is a frequent extra-renal finding. There is an association between renal involvement and HL (p= 0.009). The most frequent curve shapes: mild descending in the high frequencies and flat. There was no association between HL and age. There is no correlation between the HL and gender in this group.
