Related Experiment Video
Updated: Jun 21, 2026
06:05
Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
Published on: October 12, 2017
Female urethral diverticulum: a pathological insight
Matvey Tsivian1, Alexander Tsivian, Letizia Shreiber
1Department of Urologic Surgery, The E. Wolfson Medical Center, P.O. Box 5, Holon 58100, Israel.
Summary
Female urethral diverticula exhibit histopathological features consistent with paraurethral cysts. Avoid synthetic meshes due to infection risk; transvaginal excision is recommended over transurethral procedures.
Area of Science:
- Urology
- Pathology
- Gynecology
Background:
- Female urethral diverticula are rare conditions.
- Understanding their histopathological characteristics is crucial for diagnosis and management.
Purpose of the Study:
- To define the histopathological features of female urethral diverticula.
- To elucidate the pathogenesis and etiology of these diverticula.
Main Methods:
- Analysis of 22 clinical records of women diagnosed with urethral diverticula.
- Collection of clinical, surgical, and pathological data.
- Pathological re-assessment using hematoxylin-eosin and van Gieson stains.
Main Results:
- Predominant epithelial types included squamous, columnar, and cuboidal.
- Epithelial ulcerations were observed in nine cases.
- Diverticula walls consisted of fibrous collagen tissue, with inflammatory signs in 77.3% of specimens.
Conclusions:
- Histopathological findings align with criteria for paraurethral cysts.
- Infectious etiology suggests avoiding synthetic meshes.
- Transvaginal excision is recommended; transurethral procedures are contraindicated.
Related Concept Videos
01:27Diverticular Disease of the Colon
Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
01:22Ureters
The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...
01:16Urethra
The urethra is a hollowed tubular organ through which urine is expelled from the body. This structure extends from the bladder to the external opening, allowing urine to be released.
The anatomy of the urethra differs between males and females. In females, the urethra is short, measuring about 3–4 cm in length, and opens anterior to the vaginal opening. In males, the urethra is longer and passes through the penis, serving dual purposes: expelling urine and ejaculating semen. The male urethra is...
The anatomy of the urethra differs between males and females. In females, the urethra is short, measuring about 3–4 cm in length, and opens anterior to the vaginal opening. In males, the urethra is longer and passes through the penis, serving dual purposes: expelling urine and ejaculating semen. The male urethra is...
01:19Anatomy of the Genitourinary System II: Bladder and Urethra
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
01:28Microbiota of the Urogenital Tract
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...