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Updated: Jun 21, 2026

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43
Published on: September 11, 2020
A case report and literature review of group C streptococcal pneumonia
Guliz Erdem1, Shasta Brewer, John Harrington
1Department of Pediatrics, John A Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, USA. guliz@hawaii.edu
Abstract:
Group C streptococci rarely cause severe disease in humans. The authors report a 15-year-old girl with group C streptococcal pneumonia. No immune deficiencies were detected in our patient and investigation of virulence factors including emmL, sag A, spegg and smeZ genes failed to reveal insight into why the isolated group C streptococcal strain was so virulent. Fourteen other reports of primary group C streptococcal pneumonia were reviewed.
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