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Binding and release of consensus peptides by poly(acrylic acid) microgels
Helena Bysell1, Artur Schmidtchen, Martin Malmsten
1Department of Pharmacy, Uppsala University, SE-751 23 Uppsala, Sweden. helena.bysell@farmaci.uu.se
Biomacromolecules
|July 9, 2009
Abstract:
The interaction between positively charged consensus peptides and poly(acrylic acid) microgels was investigated with micromanipulator-assisted light microscopy and confocal laser scanning microscopy. Peptide binding and release was monitored by microgel deswelling and swelling for monodisperse multiples of heparin-binding Cardin and Weintraub motifs, (AKKARA)(n) (1
