Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
Microbes in the Production of Fermented Foods01:27

Microbes in the Production of Fermented Foods

Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Dysbiosis of the Gut Microbiota01:18

Dysbiosis of the Gut Microbiota

The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibriumโ€”referred to as dysbiosisโ€”can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Search for Bโ†’X_{s}ฮฝฮฝ[over ยฏ] Decays.

Physical review lettersยท2026
Same author

Search for Feebly Interacting Particles in B Decays with Missing Energy at Belle.

Physical review lettersยท2026
Same author

Phase I Clinical Study of DOC1021 (dubodencel) for Adjuvant Immunotherapy of Glioblastoma.

medRxiv : the preprint server for health sciencesยท2026
Same author

Constraining the Synthesis of the Lightest p Nucleus ^{74}Se.

Physical review lettersยท2025
Same author

Search for B^{0}โ†’K^{*0}ฯ„^{+}ฯ„^{-} Decays at the Belle II Experiment.

Physical review lettersยท2025
Same author

Search for a Dark Higgs Boson Produced in Association with Inelastic Dark Matter at the Belle II Experiment.

Physical review lettersยท2025
Same journal

Study of Tedizolid susceptibility among methicillin-resistant Staphylococcus aureus isolates from skin and soft-tissue infections, eastern India.

Indian journal of medical microbiologyยท2026
Same journal

Unmasking Neuroinvasive Melioidosis: Insights from Burkholderia pseudomallei Cases in an Indian Neurocenter - A Case Series.

Indian journal of medical microbiologyยท2026
Same journal

Livestock-associated antimicrobial resistance and its implications for human health in India: A one health perspective.

Indian journal of medical microbiologyยท2026
Same journal

Limited efficacy of plazomicin against carbapenemย resistant Enterobacterales in a tertiary care centre in Eastern India.

Indian journal of medical microbiologyยท2026
Same journal

Global epidemiology, genomic evolution, and clinical implications of dual- and multiple-carbapenemase-producing Klebsiella pneumoniae: A systematic qualitative review.

Indian journal of medical microbiologyยท2026
Same journal

Dual IgM seropositivity for dengue and chikungunya among suspected dengue cases: A hospital-based observational study from Northwestern Karnataka.

Indian journal of medical microbiologyยท2026
See all related articles

Related Experiment Video

Updated: Jun 21, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Probiotics.

V Gupta1, R Garg

  • 1Department of Microbiology, GMCH, Chandigarh, India. varshagupta_99@yahoo.com

Indian Journal of Medical Microbiology
|July 9, 2009
PubMed
Summary
This summary is machine-generated.

Probiotics are live beneficial bacteria that can restore gut flora disrupted by treatments like antibiotics. Careful selection and dosing are crucial for their therapeutic use in various conditions.

More Related Videos

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

Related Experiment Videos

Last Updated: Jun 21, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

Area of Science:

  • Microbiology
  • Gastroenterology
  • Immunology

Background:

  • Gut microbiota composition can be altered by medical treatments such as antibiotics, immunosuppressants, and irradiation.
  • Restoring gastrointestinal (GI) tract microbial balance with beneficial bacteria is a promising strategy for disease prevention.
  • Prebiotics selectively stimulate beneficial bacteria in the colon, and probiotics are live microorganisms conferring health benefits.

Purpose of the Study:

  • To review the role of probiotics, prebiotics, and synbiotics in modulating gut flora.
  • To discuss the clinical applications and immunological effects of probiotics.
  • To highlight considerations for the safe and effective use of probiotics.

Main Methods:

  • Literature review of studies on probiotics, prebiotics, and synbiotics.
  • Analysis of clinical evidence for probiotic efficacy in various conditions.
  • Examination of the immunological mechanisms of probiotic action.

Main Results:

  • Probiotics, including genera like Lactobacillus and Bifidobacterium, show efficacy in infantile diarrhea, antibiotic-associated diarrhea, and inflammatory bowel disease.
  • Lactobacillus rhamnosus strain GG enhances intestinal immunity by increasing IgA-secreting cells and stimulating interferon release.
  • Probiotics can facilitate antigen transport to Peyer's patches, boosting immune responses.

Conclusions:

  • Probiotics offer a potential therapeutic option for restoring gut microbial equilibrium and managing diverse health conditions.
  • Careful selection of probiotic strains, dose standardization, and understanding their effects are essential for optimal outcomes.
  • Further well-designed, placebo-controlled studies are needed to validate the health benefits of probiotics.