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Familial tularaemia.

E Peker1, A Ayaydin, N Duran

  • 1Department of Pediatrics, Medical Faculty, Mustafa Kemal University, Hatay, Turkey. pekererdal@hotmail.com

Indian Journal of Medical Microbiology
|July 9, 2009
PubMed
Summary
This summary is machine-generated.

Tularaemia, a zoonotic disease caused by Francisella tularensis, requires consideration in differential diagnoses. Early streptomycin and doxycycline treatment can lead to clinical recovery, especially in non-endemic regions.

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Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Public Health

Background:

  • Tularaemia is a zoonotic disease caused by Francisella tularensis.
  • It is typically found in endemic regions, but cases can occur in non-endemic areas.
  • Early diagnosis and treatment are crucial for favorable outcomes.

Observation:

  • Three cases of tularaemia are presented: one early-stage with fever and pharyngitis, and two with typical lymphadenitis in a non-endemic region.
  • Patients initially received non-specific treatments for upper respiratory infections without improvement.
  • Serological diagnosis was key in all three cases.

Findings:

  • One patient with early-stage disease responded to streptomycin and doxycycline.
  • Two patients with lymphadenitis received a 4-week course of antibiotics, showing good response and no complications.
  • Tularaemia should be considered in patients with fever, pharyngitis, conjunctivitis, and cervical lymphadenopathy unresponsive to beta-lactam antibiotics.

Implications:

  • This case series highlights the importance of considering tularaemia in the differential diagnosis of febrile illnesses with specific symptoms, even in non-endemic areas.
  • Prompt and appropriate antibiotic therapy, such as streptomycin and doxycycline, can effectively treat tularaemia.
  • Increased awareness among healthcare providers can lead to earlier diagnosis and improved patient outcomes.