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Updated: Jun 21, 2026

MALDI-Mass Spectrometric Imaging for the Investigation of Metabolites in Medicago truncatula Root Nodules
Published on: March 5, 2014
Imaging of metabolites by MALDI mass spectrometry
Nobuhiro Zaima1, Takahiro Hayasaka, Naoko Goto-Inoue
1Department of Molecular Anatomy, Hamamatsu University School of Medicine. zaima@hama-med.ac.jp
Abstract:
Visualization of endogenous molecules in small experimental animals is very important in order to investigate the localization of specific molecules. Conventional imaging techniques are not suitable for simultaneous visualization of endogenous molecules. We recently developed a new imaging method-imaging mass spectrometry (IMS) using matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight (MALDI-QIT-TOF). In this study, we applied IMS using MALDI-QIT-TOF to visualize the metabolites in medaka (Oryzias latipes) sections and determined the spatial distribution of metabolites including lipids.
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