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Simple renal cysts and arterial hypertension: does their evacuation decrease the blood pressure?
Enver Zerem1, Goran Imamović, Safet Omerović
1The University Clinical Center Tuzla, Trnovac bb, Tuzla, Bosnia and Herzegovina. zerem@inet.ba
Insights
Large simple renal cysts are associated with arterial hypertension. Evacuating these cysts significantly reduces blood pressure (BP), offering a potential treatment for hypertension.
Area of Science:
- Nephrology
- Cardiology
- Urology
Background:
- Arterial hypertension is a significant global health concern.
- Simple renal cysts are common, but their association with hypertension is not well understood.
- The impact of renal cyst evacuation on blood pressure requires further investigation.
Purpose of the Study:
- To investigate the relationship between simple renal cysts and arterial hypertension.
- To determine if percutaneous evacuation of renal cysts reduces blood pressure (BP).
Main Methods:
- A cross-sectional study analyzed 184 participants with renal cysts, comparing hypertensive and nonhypertensive groups based on cyst characteristics (number, size, location).
- A cross-over study evaluated BP changes in 62 hypertensive patients before and after percutaneous cyst evacuation.
- Blood pressure outcomes included systolic BP (SBP), diastolic BP (DBP), and mean BP.
Main Results:
- Giant renal cysts were significantly more prevalent in hypertensive patients (55%) compared to nonhypertensive patients (24%) (P = 0.0001).
- Percutaneous cyst evacuation led to significant reductions in SBP, DBP, and mean BP at multiple time points post-procedure (P < 0.0001).
- A notable decrease in the proportion of hypertensive patients was observed 3 days after cyst evacuation (P < 0.0001).
Conclusions:
- A significant association exists between the size of simple renal cysts and arterial hypertension.
- Percutaneous aspiration of simple renal cysts is an effective method for reducing blood pressure in hypertensive patients.
- Cyst location and number did not demonstrate a significant relationship with blood pressure levels.
Objective:
To evaluate the relationships between simple renal cysts and arterial hypertension and whether their evacuation decreases the blood pressure (BP).
Methods:
In a cross-sectional design, we analyzed 184 study participants with cysts and compared hypertensive and nonhypertensive among them. Outcomes were the number, the size and the location of a cyst. In a cross-over design, we first evaluated the change in absolute value of SBP, DBP and mean BP in 62 hypertensive patients who underwent percutaneous evacuation of a cyst and then the decrease of BP as a categorical variable that comprised all study participants.
Results:
There were 55% giant renal cysts among hypertensive and 24% among nonhypertensive patients (P = 0.0001). The prevalence rates of multiple and peripheral cysts in hypertensive and nonhypertensive patients were similar to those of single and perihilar cysts, respectively. Significant differences in SBP, DBP and mean BP were found between pretreatment readings and 3 days, 1 month, 3 months and 6 months after cyst evacuation (P < 0001). The differences were significant in all hypertensive patients (P < 0.001). There were less hypertensive patients 3 days after treatment than before treatment (P < 0.0001).
Conclusion:
An apparent association between the size of a simple renal cyst and hypertension was found, and aspiration of cysts resulted in a reduction of BP. Location and number of cysts were not related to BP.
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