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Related Experiment Video

Updated: Jun 21, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

Novel zolpidem formulations.

Richard T Owen¹

¹Medical Information Dept., Prous Science, Barcelona, Spain. scientific.prousjournals@thomsonreuters.com

Drugs of Today (Barcelona, Spain : 1998)

|July 9, 2009

Summary

This summary is machine-generated.

Novel zolpidem formulations, including extended-release, sublingual, and oral spray options, are emerging. This review examines their pharmacokinetic and pharmacodynamic effects, impacting the hypnotic market.

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Published on: December 6, 2016

Area of Science:

Pharmacology
Drug Development

Background:

Zolpidem dominates the global hypnotic market.
Several new zolpidem formulations are entering the U.S. market or are in late-stage development.

Purpose of the Study:

To review the pharmacokinetic and pharmacodynamic effects of novel zolpidem formulations.
To assess the impact of new formulations on the hypnotic drug landscape.

Main Methods:

Literature review of pharmacokinetic and pharmacodynamic data.
Analysis of recently launched and preregistered zolpidem formulations.
Comparison of extended-release, sublingual, and oral spray delivery systems.

Main Results:

New formulations include extended-release, two sublingual types, and an oral spray.
Pharmacokinetic and pharmacodynamic profiles of these novel formulations are detailed.
These advancements offer alternatives to existing zolpidem products.

Conclusions:

Novel zolpidem formulations are expanding treatment options in the hypnotic arena.
Understanding the specific effects of each formulation is crucial for clinical application.
These developments signify significant innovation in insomnia pharmacotherapy.