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Vitrectomy for endogenous fungal endophthalmitis
1Department of Ophthalmology, Ruijin Hospital, School of Medicine, The Jiaotong University, Shanghai, China. carl shen2005@yahoo.com.cn
Ocular Immunology and Inflammation
|July 9, 2009
Summary
Endogenous fungal endophthalmitis (EFE) is often caused by Candida albicans. Pars plana vitrectomy can restore useful vision in most patients with EFE, with recent surgery and IV drug use being key risk factors.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endogenous fungal endophthalmitis (EFE) is a serious intraocular infection.
- Identifying predisposing factors and optimizing treatment are crucial for visual outcomes.
Purpose of the Study:
- To evaluate predisposing risk factors for endogenous fungal endophthalmitis (EFE).
- To assess treatment outcomes for patients diagnosed with EFE.
Main Methods:
- Retrospective review of 25 patients (29 eyes) with EFE treated between 2002-2006.
- Analysis of visual acuity, recurrence rates, and causative organisms.
Main Results:
- Candida albicans was the most common pathogen (59%).
- Recent major surgery and intravenous administration were identified as common risk factors.
- Pars plana vitrectomy resulted in visual acuity of counting fingers or better in 73% of treated eyes.
Conclusions:
- Candida albicans is the leading cause of EFE.
- Prompt treatment, including pars plana vitrectomy, can lead to useful vision restoration.
- Awareness of risk factors like recent surgery and IV drug use is important for early diagnosis.
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