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Mismatch Repair

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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...

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Related Experiment Video

Updated: Jun 21, 2026

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

[Rare mutations aim toward future treatment]

Martin Ingelsson¹, Hans Basun, Frida Ekholm Pettersson

¹Uppsala universitet och geriatriska kliniken, Akademiska sjukhuset, Uppsala.

Lakartidningen

|July 10, 2009

Summary

No abstract available in PubMed .

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