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Exon 6 of human JAG1 encodes a conserved structural unit

Alessandro Pintar1, Corrado Guarnaccia, Somdutta Dhir

  • 1International Centre for Genetic Engineering and Biotechnology, Protein Structure and Bioinformatics Group, AREA Science Park, Padriciano 99, Trieste, Italy. pintar@icgeb.org

BMC Structural Biology
|July 10, 2009
PubMed
Summary

The exon 6 of Jagged-1 protein forms an independent structural unit, challenging the typical correlation between exon and domain boundaries in eukaryotic genomes. This finding impacts our understanding of gene evolution and protein structure.

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