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Updated: Jun 21, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
Published on: June 6, 2025
[Pharmacotherapy of children with depressive disorders]
H Denizot1, F Laporte, P-M Llorca
1Service de psychiatrie de l'adulte, hôpital Gabriel-Montpied, 58, rue Montalembert, 63003 Clermont-Ferrand cedex 1, France. lndenizot@yahoo.fr
Abstract:
Many reviews exist about the use of psychotropic in children with depression (American academy of child and adolescent psychiatry en 2007 [Aacap] 2007, Food and drug administration [FDA] 2004, Afssaps 2008). Antidepressants are the most important long-term treatment: only fluoxetine has been effective and is authorised in France since August 2006. The risk of suicidality and sexual maturation alteration need to be control. Psychotherapy is needed to involve efficacy and tolerability treatment. Other IRS and IRSNA are used, but another study must be conducted in currently practice condition.
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