Related Experiment Video
Updated: Jun 21, 2026

05:20
Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
Published on: March 31, 2023
Muscle fatty infiltration in rotator cuff tears: descriptive analysis of 1688 cases
Orthopaedics & Traumatology, Surgery & Research : OTSR
|July 10, 2009
Summary
Fatty infiltration (FI) in rotator cuff tears worsens with time and age. Early surgical intervention is crucial to prevent irreversible functional loss from intermediate fatty infiltration.
Area of Science:
- Orthopedic Surgery
- Musculoskeletal Imaging
- Biomedical Engineering
Background:
- Fatty infiltration (FI) significantly impacts rotator cuff repair outcomes.
- Understanding the natural history of muscle FI is vital for surgical timing.
Purpose of the Study:
- To analyze the natural history of muscle fatty infiltration (FI).
- To evaluate the onset and progression timeframe of FI in rotator cuff muscles.
Main Methods:
- Retrospective review of 1688 patient charts with rotator cuff tears.
- Preoperative CT arthrogram or MRI used to assess fatty infiltration (FI) using Goutallier's stages.
- FI assessment standardized for supraspinatus, infraspinatus, and subscapularis muscles.
Main Results:
- Significant correlation found between FI, tendon lesion type, and patient age for all studied muscles.
- FI increased significantly over time for supraspinatus and infraspinatus, but not subscapularis.
- Mean time to tendon rupture with intermediate FI was 2.5-3 years; mean time to severe FI was 3-5 years.
Conclusions:
- More extensive lesions, longer post-rupture time, and older age correlate with increased FI severity.
- Surgical intervention should precede the onset of intermediate FI to avoid irreversible functional deficits.

