Related Experiment Video
Updated: Jun 21, 2026
05:54
MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
Published on: December 13, 2017
Cognitive Impairment in Essential Tremor without Dementia
Joong-Seok Kim1, In-Uk Song, Yong-Soo Shim
1Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Journal of Clinical Neurology (Seoul, Korea)
|July 10, 2009
Summary
Essential tremor (ET) patients exhibit subclinical cognitive deficits in attention, memory, and executive functions. Age and education are key risk factors for these cognitive impairments in ET.
Area of Science:
- Neurology
- Neuropsychology
Background:
- Essential tremor (ET) is increasingly associated with cognitive deficits.
- Limited data exist on detailed neuropsychological assessments in ET patients without dementia.
Purpose of the Study:
- To conduct a case-control study on cognitive function in patients with essential tremor.
- To investigate neuropsychological deficits in ET patients without dementia.
Main Methods:
- A cohort of 34 ET patients without dementia and 33 age-matched controls were recruited.
- Participants completed a dementia-screening questionnaire and a detailed neuropsychological investigation.
Main Results:
- The ET group showed significant impairments in attention, language, verbal memory, and executive functions compared to controls.
- Specific deficits were noted in attention, verbal memory, and frontal executive functions.
Conclusions:
- Subclinical cognitive deficits, including attention, verbal memory, and executive dysfunction, are a clinical feature of ET.
- Age and educational status are significant risk factors for cognitive deficits in ET patients.
More Related Videos
07:26Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
Published on: September 26, 2019
05:58Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment
Published on: March 11, 2021
Related Concept Videos
01:22Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
01:26Alzheimer's Disease: Overview
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
01:29Alzheimer Disease l: Introduction
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
01:15Parkinson's Disease: Overview
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is to...
01:24Parkinson Disease l: Introduction
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of which...
01:30Dementia
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
The progression of dementia is generally gradual.