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Related Concept Videos

Pressure Gauges01:20

Pressure Gauges

Most pressure gauges, like those on scuba tanks, are calibrated to read zero at atmospheric pressure. Readings from such gauges are called the gauge pressure, which is the pressure relative to atmospheric pressure. When the pressure inside the tank exceeds atmospheric pressure, the gauge reports a positive value. Some gauges are designed to measure negative pressure. For example, many physics experiments must take place in a vacuum chamber, a rigid chamber from which some of the air is pumped...
Measurement of Fluid Pressure01:16

Measurement of Fluid Pressure

Fluid pressure is commonly measured using devices called manometers, which rely on liquid columns to indicate pressure differences. The height of a liquid column in a manometer reflects the pressure exerted by the fluid, providing a simple yet effective means of measurement. Different types of manometers serve specific purposes based on their configurations and the type of fluids involved.
A basic form of manometer is the piezometer, a vertical tube open at the top and filled with the same...

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Related Experiment Video

Updated: Jun 21, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Electrical microfluidic pressure gauge for elastomer microelectromechanical systems.

Emil P Kartalov, George Maltezos, W French Anderson

    Journal of Applied Physics
    |July 10, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces an electrical microfluidic pressure gauge using polydimethylsiloxane microvalves. The device estimates applied pressure by monitoring which valves close, offering a novel electrical readout for microfluidic systems.

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    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
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    Mechano-Node-Pore Sensing: A Rapid, Label-Free Platform for Multi-Parameter Single-Cell Viscoelastic Measurements

    Published on: December 2, 2022

    Area of Science:

    • Microfluidics
    • Mechanical Engineering
    • Electrical Engineering

    Background:

    • Microfluidic systems require precise pressure control for various applications.
    • Existing pressure sensing methods can be complex or incompatible with integrated microfluidics.
    • Polydimethylsiloxane (PDMS) microvalves offer tunable closing pressures based on material and geometry.

    Purpose of the Study:

    • To develop a novel electrical microfluidic pressure gauge.
    • To utilize a heterogeneous array of PDMS microvalves for pressure estimation.
    • To enable electrical readout of pressure measurements within microfluidic devices.

    Main Methods:

    • Fabrication of a heterogeneous array of PDMS microvalves with varying characteristic closing pressures.
    • Application of a uniform pressure across the microvalve array.
    • Monitoring the electrical resistance of fluid-filled channels beneath each valve to determine its closed or open state.
    • Calculating the applied pressure based on the array's state and the known closing pressures of individual valves.

    Main Results:

    • Individual PDMS microvalves demonstrated characteristic closing pressures dependent on material properties and dimensions.
    • An array of these microvalves exhibited a unique 'state' (open or closed) at a given applied pressure.
    • Electrical resistance measurements showed a significant increase (≥ 2 orders of magnitude) upon valve closure due to elastomer interruption.
    • The system successfully functioned as a pressure gauge with an electrical readout.

    Conclusions:

    • The developed electrical microfluidic pressure gauge provides an effective method for pressure sensing.
    • The device leverages the distinct closing characteristics of microvalves and electrical resistance changes for readout.
    • This technology is poised to be a critical component for active pressure-regulation in integrated microfluidic systems.