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Updated: Jun 21, 2026

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Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
Published on: October 18, 2021
Interventions for replacing missing teeth: 1- versus 2-stage implant placement
Marco Esposito1, Maria Gabriella Grusovin, Yun Shane Chew
1Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester, UK, M15 6FH.
The Cochrane Database of Systematic Reviews
|July 10, 2009
Summary
This study found no significant difference in implant or prosthesis failures between 1-stage and 2-stage dental implant procedures. However, the 1-stage approach may be preferable for partially edentulous patients, shortening treatment time.
Area of Science:
- Dental Implantology
- Oral Surgery
- Prosthodontics
Background:
- Dental implants can be placed using a 1-stage (mucosa-penetrating) or 2-stage (submerged) procedure.
- The 2-stage approach minimizes early loading but requires a second surgery and extends healing time.
Purpose of the Study:
- To compare the effectiveness of 1-stage versus 2-stage dental implant placement procedures.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials (RCTs).
- Searched Cochrane Oral Health Group's Trials Register, CENTRAL, MEDLINE, EMBASE, and contacted manufacturers.
- Included RCTs with a minimum 6-month follow-up after loading, comparing 1-stage and 2-stage procedures.
Main Results:
- Five RCTs involving 239 patients were analyzed.
- No statistically significant differences were found in prosthesis or implant failures between the two procedures.
- Trends favored the 2-stage approach in fully edentulous patients.
Conclusions:
- The limited number of patients precludes definitive conclusions.
- 1-stage procedures may be advantageous for partially edentulous patients, reducing surgical interventions and treatment duration.
- 2-stage procedures might be indicated for suboptimal primary implant stability, guided tissue regeneration, or when excessive forces are anticipated.