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Updated: Jun 21, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Obesity and renal cell carcinoma: epidemiology, underlying mechanisms and management considerations
Zachary Klinghoffer1, Brian Yang, Anil Kapoor
1Department of Surgery, Division of Urology, McMaster University, Hamilton, ON, Canada.
Abstract:
The incidence of both renal cell carcinoma (RCC) and obesity are steadily rising in Western societies. Recent studies have established that obesity is a significant risk factor for the development of several malignancies, including RCC. However, the mechanisms underlying this relationship remain to be fully elucidated. We review herein the epidemiological links between obesity and RCC, the potential mechanisms by which obesity can influence RCC development and progression, and the special considerations related to the treatment of obese patients with RCC.
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