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Updated: Jun 21, 2026

Cost-effective Method for Microbial Source Tracking Using Specific Human and Animal Viruses
Published on: December 3, 2011
Phylogenetic analysis and characterization of Korean bovine viral diarrhea viruses
Jae-Ku Oem1, Bang-Hun Hyun, Sang-Ho Cha
1Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service, Gyeonggi-do, 430-824, Republic of Korea. jku0622@nvrqs.go.kr
Abstract:
Thirty-six bovine viral disease viruses (BVDVs) were identified in bovine feces (n=16), brains (n=2), and aborted fetuses (n=18) in Korea. To reveal the genetic diversity and characteristics of these Korean strains, the sequences of their 5'-untranslated regions (5'-UTRs) were determined and then compared with published reference sequences. Neighbor-joining phylogenetic analysis revealed that most of the Korean viruses were of the BVDV subtypes 1a (n=17) or 2a (n=17). The remaining strains were of subtypes 1b (n=1) and 1n (n=1). This analysis indicates that the 1a and 2a BVDV subtypes are predominant and widespread in Korea. In addition, the prevalence of BVDV-2 was markedly higher in aborted fetuses than in other samples and was more often associated with reproductive problems and significant mortality in cattle.
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