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Updated: Jun 21, 2026

Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
Augmentation vaginoplasty of colonic neovagina stricture using oral mucosa graft
Meghan B Oakes1, Stacy Beck, Yolanda R Smith
1Department of Obstetrics and Gynecology, The University of Michigan Health System, Ann Arbor, MI 48108, USA.
Background:
Vaginal reconstruction is performed for a variety of congenital and acquired anomalies, and several techniques have been described. Conventional neovaginal reconstructions typically involve skin grafts or vascularized intestinal segments. Oral mucosa has been used successfully in urethral reconstruction, and several long-term studies have demonstrated its surgical versatility and durability.
Case Report:
Here we present the successful use of an oral mucosal graft in the surgical treatment of a strictured, colonic neovagina in a 19-year-old, 46XX female with cloacal exstrophy.
Conclusion:
Though the literature contains reports of oral mucosal grafts in primary gynecologic surgeries, this is the first report describing the use of buccal mucosa for a secondary, neovagina reconstruction. Based on the outcome of our case, we conclude that oral mucosa is a promising graft material suitable for vaginal reconstructions.
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