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Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...

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Updated: Jun 21, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Intraoperative adjuncts in surgery for primary hyperparathyroidism.

Barney J Harrison1, Frederic Triponez

  • 1Endocrine Surgery, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK. barney.harrison@sth.nhs.uk

Langenbeck'S Archives of Surgery
|July 11, 2009
PubMed
Summary
This summary is machine-generated.

Intraoperative parathyroid hormone (PTH) monitoring is recommended for primary hyperparathyroidism surgery. Evidence supporting radioguided parathyroidectomy, methylene blue, frozen section, and neuromonitoring is limited.

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Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Evidence-Based Medicine

Background:

  • Primary hyperparathyroidism (PHPT) is a common endocrine disorder.
  • Surgical intervention is the definitive treatment for PHPT.
  • Optimizing surgical techniques and adjuncts is crucial for successful outcomes.

Purpose of the Study:

  • To review the evidence base for various intraoperative adjuncts used in PHPT surgery.
  • To provide evidence-based recommendations for the use of intraoperative parathyroid hormone (PTH) monitoring, radioguided parathyroidectomy (RGP), methylene blue (MB), frozen section, and intraoperative neuromonitoring.

Main Methods:

  • A comprehensive Medline keyword search of English-language articles was conducted.
  • A draft document was developed based on the literature review.
  • The document was revised by a committee, incorporating levels of evidence and grading of recommendations.

Main Results:

  • Clear recommendations can be made for the use of intraoperative PTH monitoring during PHPT surgery.
  • There is limited evidence to support the routine use of RGP, MB, frozen section, and intraoperative neuromonitoring in PHPT surgery.

Conclusions:

  • Intraoperative PTH monitoring is a valuable tool in PHPT surgery.
  • The evidence supporting other intraoperative adjuncts is currently insufficient for widespread recommendation.