[Evaluating the degree of aging: current situations and future perspectives]

Area of Science:

• Gerontology and Longevity Research
• Biomarker Discovery
• Preventive Medicine

Context:

• Clinical aging checkups, including "Kenkou-Jyumyou Dock" and "Kokarei Dock," are increasingly practiced.
• A comprehensive aging database is being developed for the Japanese population.
• Understanding aging requires evaluating diverse indicators like genetics, cellular markers, and clinical assessments.

Purpose:

• To establish a robust database for aging research within the Japanese population.
• To investigate the standard values and intercorrelations of various aging biomarkers.
• To explore the relationship between factors such as hs-CRP, inflammatory markers, oxidative stress, and bone-vessel health.

Summary:

• The study focuses on developing a database of aging markers in Japan, encompassing genetic, cellular, and clinical data.
• Analysis includes understanding standard values and correlations between diverse factors like inflammatory markers, oxidative stress, and imaging results.
• This research aims to provide a foundational understanding for integrating anti-aging strategies into mainstream medical science.

Impact:

• Facilitates a deeper understanding of aging processes and individual aging trajectories.
• Provides crucial data for the development of personalized anti-aging interventions.
• Lays the groundwork for establishing anti-aging as a recognized and evidence-based field within medical science.