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Serum proinflammatory cytokine - interleukin-8 as possible infection site marker in preterm deliveries
Mirjana A Bogavac1, Snezana Brkić
1Department for Infection Diseases, Clinical Center Vojvodina, Novi Sad, Serbia, Serbia and Montenegro. mbogavac@yahoo.com
Journal of Perinatal Medicine
|July 14, 2009
Aim:
To evaluate serum level of proinflammatory cytokine interleukin-8 as a biochemical marker of local infections in patients with clinical symptoms of preterm deliveries.
Methods:
We studied 74 pregnant women at 24-36 gestational weeks (GW) with preterm delivery. Serum interleukin-8 was measured.
Results:
The mean value of interleukin-8 in the study group (n=36) was 19.13 pg/mL vs. 5.02 pg/mL in the controls (n=38).
Conclusions:
The results indicate that serum level of interleukin-8 might be used as non-invasive marker of infections in pregnancy, as well as a marker of preterm deliveries.