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Increased risk of acute myocardial infarction for patients with panic disorder: a nationwide population-based study

Yi-Hua Chen1, Shang-Ying Tsai, Hsin-Chien Lee

  • 1School of Public Health, Taipei Medical University, Taipei, Taiwan.

Psychosomatic Medicine
|July 14, 2009
PubMed

Insights

Individuals with panic disorder face a significantly higher risk of acute myocardial infarction within one year. This study highlights panic disorder as an independent risk factor for heart attack, emphasizing the need for integrated care.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Panic disorder is linked to coronary artery disease, but its specific association with acute myocardial infarction (AMI) risk is under-researched.
  • Understanding this link is crucial for developing targeted preventive strategies.

Purpose of the Study:

  • To prospectively investigate the association between a diagnosis of panic disorder and the subsequent risk of acute myocardial infarction (AMI).

Main Methods:

  • A nationwide, population-based cohort study utilizing the Taiwan National Health Insurance Research Database (2000-2005).
  • Included 9,641 patients diagnosed with panic disorder and 28,923 matched controls.
  • Cox proportional hazard regressions were employed, adjusting for comorbidities and sociodemographic factors.

Main Results:

  • Patients with panic disorder had a 1.75 times higher adjusted hazard of experiencing AMI within one year compared to controls (95% CI: 1.55-1.97).
  • Approximately 4.77% of panic disorder patients suffered an AMI within a year, versus 2.73% in the control group.
  • The association remained significant across strata of hypertension, coronary heart disease, and age.

Conclusions:

  • Panic disorder is an independent risk factor for acute myocardial infarction.
  • Multidisciplinary approaches are essential for optimizing the primary and secondary prevention of AMI in patients with panic disorder.
Abstract

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