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Updated: Jun 21, 2026
Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement
Published on: September 6, 2011
Porous multilayer-coated PDMS stamps for protein printing
Huaping Xu1, Alberto Gomez-Casado, Zhihua Liu
1Molecular Nanofabrication Group, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands. xuhuaping@mail.tsinghua.edu.cn
Abstract:
A polyelectrolyte multilayer was assembled on top of a patterned PDMS stamp employing the layer-by-layer (LbL) assembly technique. By post-treatment with a base and further cross-linking, a porous multilayer-coated PDMS composite stamp was obtained. With the pore structures acting as an ink reservoir, the multiple printing of proteins was successfully achieved without the need to re-ink the stamp.
