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Updated: Jun 21, 2026

Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse
Published on: August 30, 2022
Severe mitral and aortic regurgitation in association with ankylosing spondylitis
Matthew Luckie1, Luciane Irion, Rajdeep S Khattar
1Manchester Heart Centre, Manchester Royal Infirmary, Manchester, United Kingdom.
Abstract:
Aortic disease and aortic valve regurgitation are well documented in association with ankylosing spondylitis, although involvement of the mitral valve occurs more rarely. We report a case of severe mitral and aortic regurgitation in association with ankylosing spondylitis. We then discuss the characteristic cardiac manifestations that may occur in association with ankylosing spondylitis and the associated echocardiographic features.
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