[Coronary artery bypass grafting in patients over 70 years old]
Hong-yin Li1, Qing-yu Wu, Ming-kui Zhang
1Department of Cardiac Surgery, First Hospital of Tsinghua University, Beijing 100016, China.
Insights
Coronary artery bypass grafting (CABG) in patients over 70 years old shows similar efficacy to younger patients. Both conventional CABG and off-pump CABG are effective, with no significant differences in outcomes.
Area of Science:
- Cardiovascular Surgery
- Geriatric Cardiology
- Thoracic Surgery
Context:
- Coronary artery bypass grafting (CABG) is a common procedure for treating coronary artery disease.
- Elderly patients (over 70 years) present unique challenges and considerations for cardiac surgery.
- Evaluating the safety and efficacy of CABG in this specific demographic is crucial for optimizing patient care.
Purpose:
- To retrospectively analyze the experiences, indications, technique, and results of coronary artery bypass grafting (CABG) in patients over 70 years old.
- To compare outcomes between conventional CABG (CCABG) and off-pump CABG (OPCAB) in elderly patients.
- To assess the feasibility and effectiveness of achieving full revascularization in this population.
Summary:
- Ninety-one patients aged 70-83 underwent CABG (72 CCABG, 19 OPCAB).
- High utilization of left internal mammary artery (96.7%).
- No significant differences in in-hospital mortality, cerebral infarction, pulmonary infection, intubation time, ICU stay, respiratory, or renal failure between CCABG and OPCAB groups. CCABG involved more grafts (P < 0.01).
- Postoperative follow-up (3-36 months) showed one case of recurrent angina in the OPCAB group.
Impact:
- Coronary artery bypass grafting (CABG) in patients over 70 years old can achieve efficacy comparable to younger patients.
- Both conventional and off-pump CABG demonstrate similar safety and effectiveness profiles in the elderly.
- The findings support the strategy of full revascularization to improve myocardial blood supply in elderly patients with coronary artery disease.
Objective:
To retrospectively analyze the experiences, indications, technique, and results of coronary artery bypass grafting (CABG) in patients over 70 years old.
Methods:
Ninety-one patients received coronary artery bypass grafting from March 2004 to March 2008. Ages ranged from 70 to 83 years old, 22 patients over 75 years old. Conventional CABG (CCABG) in 72 patients, off-pump CABG (OPCAB) in 19 patients. Clinical data has no significant differences in two groups. The rate of using left internal mammary artery was 96.7%. The number of grafts in CCABG and OPCAB group were 2 to 5 (3.5 +/- 0.8) and 1 to 4 (2.9 +/- 0.7) respectively.
Results:
In-hospital death in 2 cases, both were from chronic obstructive pulmonary disease and pulmonary infection. Cerebral infarction in 1 case and pulmonary infection in 2 cases in CCABG group, but no significant difference between two groups, and no difference in intubation, ICU stay, respiratory failure, renal function failure. But number of grafts in CCABG was significantly more than that in OPCAB (P < 0.01). Postoperative follow-up was 3 to 36 months, 1 case with recurrent angina in OPCAB.
Conclusions:
According to the characteristic of coronary artery disease in elderly, fully revascularization and improving myocardial blood supply, patients over 70 years old with CABG can obtain the same efficacy as younger patients. There were not significant difference between CCABG and OPCAB.
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