Related Experiment Video
Updated: Jun 21, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
Published on: April 15, 2021
[Relationship between characteristic geometry and risk of rupture in cerebral saccular aneurysm]
Jian-ping Song1, Ying Mao, Dong-lei Song
1Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Objective:
To explore the relationship between the characteristic geometry and the risk of rupture in cerebral saccular aneurysm.
Methods:
The clinical features of 473 cerebral saccular aneurysm patients with complete materials of cerebral angiography, 426 with ruptured aneurysm and 47 with unruptured aneurysm, were analyzed retrospectively. The relation of depth, neck width, and aspect ratio (AR) of aneurysms to the risk of rupture were analyzed.
Results:
The mean depth, neck width, and the AR of the patients with ruptured aneurysm were (5.9+/-3.0) mm, (3.0+/-1.2) mm, and (2.1+/-0.9), all significantly lower than those of the unruptured aneurysm patients [(8.0+/-4.2) mm, (4.8+/-2.4) mm, and (1.7+/-0.6) respectively, all P<0.01].
Conclusion:
AR is not correlated with the location of aneurysms, but reflects the geometrical and hemodynamic features of cerebral saccular aneurysms very well. High AR may be useful in predicting imminent aneurysmal rupture. But by now, no definitive AR level is accepted in discriminating between unruptured and ruptured aneurysms.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm I: Introduction
Hemorrhagic Stroke l: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Deformation in a Circular Shaft
Deformations in a Symmetric Member in Bending
When the member is segmented into tiny cubic elements, it is observed that the primary stress...
