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Updated: Jun 21, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
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Published on: June 10, 2025

Hypertrophic lupus erythematosus: case report.

Ivana Bardek1, Aleksandra Basta-Juzbasić, Branka Marinović

  • 1University Department of Dermatology and Venereology Zagreb University Hospital Center and School of Medicine, Zagreb Croatia. ivanabardek@yahoo.com

Acta Dermatovenerologica Croatica : ADC
|July 15, 2009
PubMed
Summary

Discoid lupus erythematosus (DLE) is a common autoimmune skin condition affecting women aged 20-40. This case highlights rapid treatment success with antimalarials and topical corticosteroids.

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Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
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Published on: June 10, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Area of Science:

  • Dermatology
  • Immunology
  • Autoimmune Diseases

Background:

  • Discoid lupus erythematosus (DLE) is the most prevalent form of cutaneous lupus erythematosus.
  • It predominantly affects women aged 20-40, triggered by genetic predisposition and factors like UV radiation, stress, and infections.

Observation:

  • Lesions typically manifest on sun-exposed areas, including the face, upper back, chest, and extremities.
  • Characterized by erythema, hyperkeratosis, and atrophy, DLE presents a significant dermatological challenge.

Findings:

  • The presented case involves lupus erythematosus hypertrophicus, a variant of DLE.
  • Rapid and effective treatment outcomes were achieved using a combination of antimalarials and topical corticosteroids.

Implications:

  • This case underscores the efficacy of combined antimalarial and topical corticosteroid therapy for DLE.
  • Early diagnosis and prompt treatment are crucial for managing DLE and improving patient outcomes.