Related Experiment Videos
A Plasmodium falciparum exo-antigen alters erythrocyte membrane deformability
K M Naumann1, G L Jones, A Saul
1Department of Biochemistry, University of Queensland, Australia.
FEBS Letters
|November 4, 1991
Abstract:
Here we describe a reduced membrane deformability of human erythrocytes when aspirated into 0.6 microns diameter in polycarbonate sieves, after exposure of uninfected cells to spent parasite-culture supernatant. This, taken in concert with a previous observation that intra-erythrocytic development of the parasite P. falciparum decreases host localised membrane deformability, may indicate a biological role for such parasite-induced changes in the rheological properties of the erythrocyte.