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Updated: Jun 21, 2026
09:41
Imaging Centrosomes in Fly Testes
Published on: September 20, 2013
Centrioles in flies: the exception to the rule?
Delphine Gogendeau1, Renata Basto
1Compartimentation et Dynamique Cellulaires, UMR144 CNRS-Institut Curie, 12 rue Lhomond, 75005 Paris cedex 05, France.
Seminars in Cell & Developmental Biology
|July 15, 2009
Summary
Centrioles and basal bodies are microtubule-based cell structures crucial for organizing cell division and forming cilia. Their roles in animal development are explored using Drosophila melanogaster.
Area of Science:
- Cell Biology
- Developmental Biology
- Structural Biology
Background:
- Centrioles and basal bodies are microtubule-based structures with ninefold symmetry.
- Centrioles organize centrosomes for microtubule nucleation.
- Basal bodies facilitate cilia and flagella assembly.
Purpose of the Study:
- To review the function of centrosomes and cilia in Drosophila melanogaster development.
- To discuss the implications of these findings for other model organisms.
Main Methods:
- Literature review focusing on centrosome and cilia research.
- Analysis of studies in Drosophila melanogaster as a model organism.
Main Results:
- Centrosomes and cilia play vital roles in cell and tissue organization.
- Specific contributions to animal development are still being established.
- Drosophila melanogaster serves as a key model for studying these organelles.
Conclusions:
- Centrosomes and cilia are fundamental to cellular architecture and function.
- Further research is needed to fully elucidate their developmental roles across species.
- Drosophila research provides valuable insights into conserved biological processes.
Related Concept Videos
01:13Centrioles and Centrosomes
Most animal cells comprise a pair of centrioles together called a centrosome. The cell duplicates its centrosome and contains two centrosomes side-by-side, which begin to move apart during the prophase. As the centrosomes migrate to two different sides of the cell, microtubules start extending from each centrosome toward the other end. The mitotic spindle is composed of the centrosomes and their emerging microtubules.
Near the end of the prophase, also called late prophase or "prometaphase,"...
Near the end of the prophase, also called late prophase or "prometaphase,"...
02:25Centrosome Duplication
The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
02:25Centrosome Duplication
The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
01:24Microtubules in Cell Motility
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
02:13Determining the Plane of Cell Division
Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function.
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
02:45The Ratio of X Chromosome to Autosomes
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...